The complement system is the first line of defense against infection, and is thus a critical step in maintaining biological health in response to invading pathogens. However, uncontrolled activation of complement – occurring commonly as a sequela to a number of diseases including kidney transplant, immune-complex mediated glomerulonephritis (lupus nephritis, membranous nephropathy), myasthenia gravis, neuromyelitis optica, multiple sclerosis, Alzheimer’s disease, and autoimmune uveitis – can lead to host cell injury and ultimately end organ damage, creating a significant medical burden in a large population of already compromised individuals.
Although the therapeutic role for complement blockade is not clear, it is an active area of research. This symposium will focus on novel insights into the complement pathway in a number of clinical disorders and offer potential therapeutic implications
Call for Abstracts:
Abstract submissions are invited for a poster session. For complete submission instructions, please send an email to Complement2017@nyas.org with the words "Abstract Information" in the subject line. The deadline for abstract submission is February 24, 2017.