Nutritional conditions in early life may, through epigenetic and epigenesist processes, have profound effects on physiological functioning and health in later life. This course aims to provide a detailed scientific background on the mechanisms that may underlie these early-life effects, both at the physiological and gene expression level. The program combines knowledge on perinatal programming by nutritional factors in humans, laboratory and farm animals.
The course is aimed at postgraduates (MSc, PhD) with a background in animal, biological, health, or food sciences and open for participants from both industry and universities/research centers. Participants are invited to present their own work (poster or oral presentation) and challenged to actively contribute
The course consists of:
A series of lectures by national and international experts from different disciplines providing the latest scientific knowledge on the different subjects.
A hands-on workshop where participants can learn more on Pyrosequencing (DNA methylation), Droplet PCR (miRNA) or genome-wide DNA methylation analysis.
Discussions on the participants own research projects. The course consists of a series of lectures providing the latest scientific knowledge on the different subjects. Furthermore, this knowledge will be discussed in several workshops with emphasis on application of the theory.
The following topics will be addressed:
Early life nutrition
Prenatal programming; mechanisms and implications
Hunger winter studies
Nutrition during pregnancy
Maternally-mediated immunological imprinting
Effects of the microbioom
DNA methylation, histone modifications and ncRNA
State of the art techniques
Statistical and bioinformatic analysis
Dietary interventionsto discussions.
Dr. Wilma Steegenga; Division of Human Nutrition, Wageningen University and Research, NL
Prof. Bas Zwaan; Genetics, Wageningen University and Research, NL
Prof. Bas Kemp; Adaptation Physiology, Wageningen University and Research, NL
Dr. Elmar Tobi; Human Nutrition, Wageningen University and Research, NL
Dr. Aart Lammers; Adaptation Physiology, Wageningen University and Research, NL
Dr. Fred van Leeuwen; Netherlands Cancer Institute, Amsterdam, NL
Dr. Torsten Pl�sch; University Medical Centre Groningen, NL
Prof. Paul de Vos; University Medical Centre Groningen, NL
Dr. Mona Mischke; Nutricia Research, NL
Dr. Charlotte Ling; Lund University, SE
Dr. Carlos Guerrero-Bosagna; Link�ping University, SE
Dr. Bas Heijmans; Leiden University Medical Centre, NL
Date & duration
The course is scheduled for 31 May – 2 June 2017.
The course language will be English.
The course fee (which includes materials, coffee/tea during breaks, lunches and one course dinners (Wednesday) but cover accommodation) depends on the participant’s affiliation:
PhD candidates affiliated with VLAG / WIAS
University staff / Non-profit
Industry / For-profit