Past Event

Epigenesis and Epigenetics - Physiological consequences of perinatal nutritional programming

31 May – 2 June 2017
Wageningen, Netherlands
 

Course aim

Nutritional conditions in early life may, through epigenetic and epigenesist processes, have profound effects on physiological functioning and health in later life. This course aims to provide a detailed scientific background on the mechanisms that may underlie these early-life effects, both at the physiological and gene expression level. The program combines knowledge on perinatal programming by nutritional factors in humans, laboratory and farm animals.


 

Target group

The course is aimed at postgraduates (MSc, PhD) with a background in animal, biological, health, or food sciences and open for participants from both industry and universities/research centers. Participants are invited to present their own work (poster or oral presentation) and challenged to actively contribute

Course design

The course consists of:

  • A series of lectures by national and international experts from different disciplines providing the latest scientific knowledge on the different subjects.
  • A hands-on workshop where participants can learn more on Pyrosequencing (DNA methylation), Droplet PCR (miRNA) or genome-wide DNA methylation analysis.
  • Discussions on the participants own research projects. The course consists of a series of lectures providing the latest scientific knowledge on the different subjects. Furthermore, this knowledge will be discussed in several workshops with emphasis on application of the theory.

Programme topics

The following topics will be addressed:

Early life nutrition

  • Prenatal programming; mechanisms and implications
  • Hunger winter studies
  • Nutrition during pregnancy

Immune programming

  • Maternally-mediated immunological imprinting
  • Effects of the microbioom

Epigenetics

  • DNA methylation, histone modifications and ncRNA
  • State of the art techniques
  • Statistical and bioinformatic analysis

Phenotypic plasticity

  • Metabolic flexibility
  • Dietary interventionsto discussions.

Organization

Course coordinators

  • Dr. Wilma Steegenga; Division of Human Nutrition, Wageningen University and Research, NL
  • Prof. Bas Zwaan; Genetics, Wageningen University and Research, NL

Other faculty

Prof. Bas Kemp; Adaptation Physiology, Wageningen University and Research, NL

Dr. Elmar Tobi; Human Nutrition, Wageningen University and Research, NL

Dr. Aart Lammers; Adaptation Physiology, Wageningen University and Research, NL

Dr. Fred van Leeuwen; Netherlands Cancer Institute, Amsterdam, NL

Dr. Torsten Pl�sch; University Medical Centre Groningen, NL

Prof. Paul de Vos; University Medical Centre Groningen, NL

Dr. Mona Mischke; Nutricia Research, NL

Dr. Charlotte Ling; Lund University, SE

Dr. Carlos Guerrero-Bosagna; Link�ping University, SE

Dr. Bas Heijmans; Leiden University Medical Centre, NL

Date & duration

The course is scheduled for 31 May – 2 June 2017.

Language

The course language will be English.

Course fee 

The course fee (which includes materials, coffee/tea during breaks, lunches and one course dinners (Wednesday) but does not cover accommodation) depends on the participant’s affiliation:

                                                          Course Fees
PhD candidates affiliated with VLAG / WIAS € 185,-
PhD candidates € 375,-
University staff / Non-profit € 750,-
Industry / For-profit € 1300,-

 

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