Past Event

3rd DNA Replication/Repair Structures and Cancer Conference

11–15 February 2018
Cancun, Mexico

Join us for the third Fusion conference on DNA Replication/Repair Structures and Cancer. The meeting will take place from the 11-15 February 2018 in Cancun, Mexico where participants will discuss structural and mechanistic insights into dynamic protein, chromatin, DNA and RNA complexes acting in DNA replication and repair events relevant to cancer. 

Key Sessions 

Repair and replication complexes, structures and mechanisms

Mutational signatures, kataegis, DNA repair, and cancer

Damage signaling, pathway selection & cross-talk

Targeting synthetic lethality and essentiality for damage responses

Chromatin and chromosome instability

Epigenetics, DNA damage and repair

PARP, PARG, and metabolic signaling

Mitochondrial replication/repair and damage signaling

RNA damage responses and actions in repair

DNA repair, apoptosis and cancer


John Tainer (Director of SIBYLS at LBL, Robert A. Welch Chair in Chemistry at MD Anderson Cancer Center) & Tom Blundell (Director of Research, University of Cambridge)

Keynote Speakers

Steve Jackson (University of Cambridge)

Bruce Stillman (CSHL)

Steve West (The Francis Crick Institute)

Serena Nik-Zainal (Wellcome Trust Sanger Institute) 

Invited Speakers

Lorena Beese (Duke University Medical Center)

Simon Boulton (The Francis Crick Institute)

Chris Brosey (MD Anderson Cancer Center)

Cynthia Burrows (University of Utah)

Jean-Baptiste Charbonnier (University Paris‐Saclay)

Walter Chazin (Vanderbilt University)

Karlene Cimprich (Stanford University School of Medicine)

David Cortez (Vanderbilt University)

Sheila David (University of California, Davis)

Michelle Debatisse (Gustave Roussy Institute)

Sylvie Doublie (University of Vermont)

Jessica Downs (Institute of Cancer Research)

Brandt Eichman (Vanderbilt University)

Dorothy Erie (University of North Carolina)

Ilya Finkelstein (University of Texas at Austin)

Marco Foiani (University of Milan)

Mark Glover (University of Alberta)

Jane Grasby (Krebs Institute)

Jim Haber (Brandeis University)

Samir Hamdan (KAUST)

Reuben Harris (University of Minnesota)

Karl-Peter Hopfner (Ludwig-Maximilians-University Munich)

Ben Van Houten (University of Pittsburgh)

Meindert Lamers (MRC Laboratory of Molecular Biology)

Susan Lees-Miller (Arnie Charbonneau Cancer Institute)

Karolin Luger (University of Colorado at Boulder)

Mauro Modesti (Cancer Research Center of Marseille)

Zachary Nagel (Harvard University)

Mark O'Connor (AstraZeneca)

John Pascal (Universite de Montreal)

Tanya Paull (University of Texas at Austin)

Luca Pellegrini (University of Cambridge)

Phoebe Rice (University of Chicago)

Andrej Sali (University of California, San Francisco)

Orlando Scharer (Ulsan National Institute of Science and Technology)

Katharina Schlacher (MD Anderson Cancer Center)

Titia Sixma (NKI)

Maria Spies (University of Iowa)

Terence Strick (Institut Jacques Monod)

Madalena Tarsounas (The CR-UK/MRC Oxford Institute for Radiation Oncology)

Susan Tsutakawa (Lawrence Berkeley National Laboratory)

Ashok Venkitaraman (University of Cambridge)

Dale Wigley (Imperial College London)

Scott Williams (NIEHS)

Wei Yang (NIH)

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