The ECCO-AACR-EORTC-ESMO Workshop on Methods in Clinical Cancer Research is an educational programme that introduces junior clinical oncologists in any oncology subspecialty to the principles of good clinical trial design. In 2018, we will be celebrating 20 editions of this well-recognised and CME accredited Workshop. Over 1500 investigators have been trained at this Workshop, many of whom transformed into current world class experts pushing the boundaries of cancer research and therapy. One of the key benefits of the MCCR Workshop is exclusive access to and mentoring by up to 40 highly experienced clinical experts in the field of oncology from Europe, US and Canada. Under one roof, participants can engage with a multidisciplinary faculty, with expertise across the spectrum of cancers, to guide them through the complex and changing cancer research landscape to advance therapies which meet patients’ needs.